As a child Sakura Mamiya mysteriously disappeared in the woods behind her grandma's home. She returned whole and healthy, but since then she has had the power to see ghosts. Now a teenager, she just wishes the ghosts would leave her alone! At school, the desk next to Sakura's has been empty since the start of the school year, then one day her always-absent classmate shows up, and he's far more than what he seems!

Godai is a ronin (someone who has failed university entrance exams) living in a run down apartment house called Maison Ikkoku. Among the other residents are the nosy Ichinose, the sexy Akemi Roppongi, and the mysterious Yotsuya. The others are given to having wild parties which makes it difficult for Godai to study. Into this mayhem comes the recently widowed Kyoko as the new live-in manager. Godai falls for her, but doesn't have the nerve to tell her. As time passes, their relationship slowly develops amid life at Maison Ikkoku, despite all sorts of romantic hurdles.

Kō Kitamura, whose family owns a sporting goods store, has known the Tsukishima girls since he was born. The Tsukishima family runs a batting center and cafe, and they have four daughters. There's Ichiyo, the responsible eldest; Wakaba, Kō's cheerful best friend; Aoba, who doesn't get along with Kō; and Momiji, the energetic youngest daughter. When Kō enters high school, he aspires to lead his baseball team to the Koshien National High School Championship as their ace pitcher and make Wakaba's dream come true.

The incidents which occurred on August 14th and 15th bring a group of young boys and girls together… They are members of a group they call themselves the "Mekakushi Dan" (Blindfold Organization) and each member possesses a strange power involving their eyes.

On Christmas Eve, Hiro Hirono meets a girl named Miyako Miyamura as she chases a purse snatcher. Hiro later finds out that Miyako also goes to the same school as he does and they start hanging out together. This makes Hiro's childhood friend, Kei Shindō, feel left out, so she tries to compete with Miyako for Hiro's affection, creating a love triangle. Meanwhile, Renji Asō meets a girl named Chihiro Shindō at an abandoned train station. He soon learns that Chihiro suffers from a type of amnesia where her memory lasts for only 13 hours. He also discovers Chihiro's dream of writing a novel, but she has never been able to fulfill that dream due to her condition. Renji then decides to help her fulfill that dream.

There are twisted tales and twisted tales, but few are as twisted as poor Sado's, who's just realized that he actually likes being made miserable. Of course, knowing that only makes him more miserable, which in turn... well, you get the idea. Desperate to break the circle, Sado volunteers for a special club where he hopes he can work through his issues only to discover that the other members have equally... complex... issues to deal with. For example, the hyper-aggressive club president Isurugi not only has a violent fear of cats, but also believes herself to be a god! Then there's Yuno, who's terrified of men; the Nurse, who forces other people to perform cosplay; and Hayama, Sado's best friend and a compulsive cross-dresser, who's also the girl that Sado is infatuated with. (We did say it was complex, remember?)

Adorable young Akiko is thrilled to be reuniting with Akito, the handsome older brother she hasn’t seen in years! In fact, she might be a little too excited about living under the same roof with her precious big bro. This pint-sized cutie has a serious brother complex, and she’s definitely not interested in sharing his attention. Unfortunately for little sister, she and Akito won’t be living alone: three gorgeous girls from the student council will be along for the ride! So much for the peaceful existence Akito was craving. Big Brother the dreamy will have to stay on his toes to avoid the advances of Sis and her ravishing rivals!

Teenager Hata Kosaku is crushed when his favorite singing idol, Kusakabe Yuka, stuns the world by retiring from show business. Kosaku’s friends try to cheer him up, but nothing can chase away his gloomy mood until Yuka herself transfers into his class at Tamo Agriculture School!

Ogata Satoko is a 39 years-old woman. She is happily enjoying the single life. However, things change after an alumni reunion wher she's the last single and a meet with Okamura Keitaro.