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When Simon awakens in the hospital after surviving a near-fatal accident, amnesia has erased the last two years from his memory. He learns that his brother was killed, he has married a woman he doesn't remember and he's haunted by strange visions of the woman he loved.

When Dr. Anthony Edwardes arrives at a Vermont mental hospital to replace the outgoing hospital director, Dr. Constance Peterson, a psychoanalyst, discovers Edwardes is actually an impostor. The man confesses that the real Dr. Edwardes is dead and fears he may have killed him, but cannot recall anything. Dr. Peterson, however is convinced his impostor is innocent of the man's murder, and joins him on a quest to unravel his amnesia through psychoanalysis.

After a car crash, criminal psychologist Dr. Miranda Grey regains consciousness only to find that she's a patient in the same mental institution that currently employs her. She's been accused of murdering her husband Dr. Douglas Grey — but she has no memory of committing the crime. As she tries to regain her memory and convince her co-worker, Dr. Pete Graham, of her innocence, a vengeful spirit uses her as an earthly pawn, which further convinces everyone of her guilt.

While undergoing heart surgery, a man experiences a phenomenon called ‘anesthetic awareness’, which leaves him awake but paralyzed throughout the operation. As various obstacles present themselves, his wife must make life-altering decisions while wrestling with her own personal drama.

Liam wakes from a car crash with no memory of who he is. As he makes his way into town to look for help, he finds only dead bodies, all with strange pale eyes. Liam's first assessment is that a virus is present in the air, but he soon discovers the horrible truth: anyone who comes within a 50-foot radius of him dies instantly.

Dan Merrick comes out from a shattering car accident with amnesia. He finds that he is married to Judith who is trying to help him start his life again. He keeps getting flashbacks about events and places that he can't remember. He meets pet shop owner and part time private detective Gus Klein who has supposedly done some work for him prior to the accident. Klein helps Merrick to find out more...

In this documentary, Alex trusts his twin, Marcus, to tell him about his past after he loses his memory. But Marcus is hiding a dark family secret.

David Aames has it all: wealth, good looks and gorgeous women on his arm. But just as he begins falling for the warmhearted Sofia, his face is horribly disfigured in a car accident. That's just the beginning of his troubles as the lines between illusion and reality, between life and death, are blurred.